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Post# of 251748
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Re: Titan V post# 216631

Tuesday, 01/16/2018 6:23:39 PM

Tuesday, January 16, 2018 6:23:39 PM

Post# of 251748
"Median OS was 10.2 months with cabozantinib versus 8.0 months with placebo (HR 0.76; p=0.0049).

Median progression-free survival (PFS) was more than doubled, at 5.2 months with cabozantinib and 1.9 months with placebo (HR 0.44; p<0.0001).

Objective response rates per RECIST 1.1 were 4 percent with cabozantinib and 0.4 percent with placebo (p=0.0086)."

It is interesting that PFS was increased by 3.3 months whether OS was increased by just 2.2 months.

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