Followers | 17 |
Posts | 936 |
Boards Moderated | 0 |
Alias Born | 04/26/2010 |
![](http://investorshub.advfn.com/images/default_ih_profile2_4848.jpg?cb=0)
Tuesday, January 09, 2018 1:09:20 PM
I just takes an effort to lift ones mental ass off from the whiny chair and do something called estimating. Lemme show you how:
We know that there were 6 subjects (0.462 * 13 = 6) in prurisol 200 mg group with IGA 3 that had 2 point drop. Numbers for 200 mg ITT group were 28 subjects and 18 of them were IGA 3. Let's be stingy and assume that the seventh 2 point drop in ITT did not happen in IGA 3 group. We get:
prurisol 200 mg ITT IGA 3 - 2 point change percentage: 100*6 /18 = 33.3 % (at least)
Placebo group had ITT of 30 out which 23 was IGA 3. This group had 4 subjects with 2 point IGA drop. Let's be generous and assume that all four happened in IGA 3 subjects. That means
placebo ITT IGA 3 - 2 point change percentage: 100*4/23 = 17.4 % (at most)
Risk ratio associated with 2 point drop in IGA 3 groups: 0.52 for prurisol (and probably better). A number that is known to imply clear statistical significance in 100+ subjects trials.
BTW:In Esteem 2 trial Otezla scored PASI 75 percentage of 28.8 % when calculated using LOCF. Prurisols results in p2a are probably better than that. Strange: It looks like Leo did not lie, but famous Adam F. might have. Who would have thunk THAT!
Recent IPIX News
- Form 8-K - Current report • Edgar (US Regulatory) • 02/01/2024 01:30:25 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 12/05/2023 09:25:58 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/20/2023 09:05:44 PM
- Form NT 10-Q - Notification of inability to timely file Form 10-Q or 10-QSB • Edgar (US Regulatory) • 11/15/2023 01:00:19 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/30/2023 08:15:25 PM
- Form 10-K - Annual report [Section 13 and 15(d), not S-K Item 405] • Edgar (US Regulatory) • 09/28/2023 01:00:08 PM
FEATURED BNCM and DELEX Healthcare Group Announce Strategic Merger to Drive Expansion and Growth • Jul 2, 2024 7:19 AM
EWRC's 21 Moves Gaming Studios Moves to SONY Pictures Studios and Green Lights Development of a Third Upcoming Game • EWRC • Jul 2, 2024 8:00 AM
NUBURU Announces Upcoming TV Interview Featuring CEO Brian Knaley on Fox Business, Bloomberg TV, and Newsmax TV as Sponsored Programming • BURU • Jul 1, 2024 1:57 PM
Mass Megawatts Announces $220,500 Debt Cancellation Agreement to Improve Financing and Sales of a New Product to be Announced on July 11 • MMMW • Jun 28, 2024 7:30 AM
VAYK Exited Caribbean Investments for $320,000 Profit • VAYK • Jun 27, 2024 9:00 AM
North Bay Resources Announces Successful Flotation Cell Test at Bishop Gold Mill, Inyo County, California • NBRI • Jun 27, 2024 9:00 AM