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Friday, January 05, 2018 11:00:25 AM
The Science Story
Fact number 1: Typical duration of radiation treatment in head and neck cancer is about 50 days.
Fact number 2: In OM trial 93 % of severe OM incidents in placebo arm occurred ON OR BEFORE day 40
Fact number 3: In OM trial 71 % of severe OM incidents in Brilacidin arm happened ON OR AFTER day 40
Fact number 4: For the typical radiation treatment period hazard ratio for Brilacidin over placebo is better than 0.45.
Fact number 5: A bulk of censors happened well after the radiation treatment period.
Fact number 6: The risk of developing a severe OM drops drastically in few weeks after radiation treatment.
Fact number 7. Brilacidin downregulates hTRPV1 ion channel associated with sensitivity to capsaicin and heat.
Fact number 8. Brilacidin upregulates hTRPA1 ion channel associated with sensitivity with cold.
The Science fiction story in case you still are fussing about censors and just for fun.
Patient Creamy: “So the hell weeks are over – no more radiation, just the monotony of swishing brilacidin and dripping chemo. Oh man, I am getting an urge for ice cream.But, the last time I ate it, it was hurting cold. Yeah, must be that swish stuff. To hell with swishing, I am going to have myself a quart of Haagen Dazs Mint.”
Patient Hotty: “I hear you Creamy - you go for it. Did I tell you my brother-in-law is one full sized sadistic moron. Can you believe this? He managed to fool me into eating chili peppers just few weeks ago - with all those freaking ulcers still in my mouth. The strange thing – it did not burn that much. Mr. Moron looked disappointed. Maybe it was that swishing stuff. Dunno, but as long as the family sadist keeps visiting I keep swishing.”
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