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Thursday, December 28, 2017 8:56:09 AM
The only way to detect that arteries are vulnerable to
atherosclerosis is to assess endothelial function. This is a
test of the endothelial cells that line all the arteries in the body.
The endothelium is the single layer of cells that line various
organs and cavities, especially the heart, blood and lymphatic
vessels. These cells act as a shield, preventing plaque from
forming inside the artery wall, and produce substances that
stop blood clots from developing in the vessel.
Healthy endothelial cells release nitric oxide (NO), which
is responsible for most of the protective functions of these
cells in the artery.
In an at-risk individual, the endothelial cells do not
produce enough NO, or the NO produced is deactivated
by chemicals in the bloodstream before it can prevent
deposits from forming in the arterial wall.
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