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Re: loanranger post# 208683

Sunday, 12/17/2017 10:17:46 PM

Sunday, December 17, 2017 10:17:46 PM

Post# of 402818
So Otezla Extreem 1 & 2 resulted in a placebo PASI 75 of around 5.5%. As a trial sponsor you get a blinded case reports showing an overall PASI 75 rate of say ... 40%...what do you think? Possibly the drug is efficacious. Would you expand trial sites? What number do you think frugal Leo needed to see? He saw something, or there would not have been a site expansion early last summer.
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