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Re: DaubersUP post# 208041

Wednesday, 12/13/2017 4:34:45 PM

Wednesday, December 13, 2017 4:34:45 PM

Post# of 403035
"I'm not sure what the confusion is."

There shouldn't be any. To conclude that B prevented the disease in 63% of the PP population that was treated with Brilacidin one would also have to conclude that the placebo prevented the disease in 40% of the PP population given the placebo.

The company doesn't say that and they don't say it because they can't show it to be true. It would only be theoretically true if it could be shown that 100% of the people who were given the drug would have developed the disease if they weren't given the drug.

"Incidence of severe OM in Per Protocol (PP) Population: Brilacidin 36.8%, Placebo 60.0%."

Even if there was no placebo arm and the the Brilacidin results were the same I believe that the proper description of the results would be that the disease did not occur in 63% of the population, not that Brilacidin prevented the occurrence of the disease in 63% of the treated individuals. I hope you can appreciate the difference.

You know that I know diddly about this stuff, but I think the logic of the point is hard to refute.




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