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Re: XenaLives post# 5476

Monday, 12/11/2017 3:49:22 PM

Monday, December 11, 2017 3:49:22 PM

Post# of 21544
That's not what our MOA nor our team of experts "believe" nor apparently George Perry. Will be interesting to see if Fragile X can prove that out as I believe that could be our quickest route to demonstrate efficacy of synapses repair. Nor do Jenni's parents or the well documented CU patients feel that way. Maybe not even many of the relatives of patients in this recent study. Hopefully we'll see soon enough. I don't doubt for a minute (even though Dr Alkon may disagree) that the worse synaptic damage the less likelihood of large improvement. If that's the case maybe the study will show better improvement in those with scores a few points higher than those essentially at zero. Maybe that will be shown. Maybe it just takes a little longer than 8-12 weeks of treatment as the CU documentation shows. Still questions, no doubt. There is also no doubt that the patients in our study indeed had AD. In mild to moderate case studies, that isn't a 100% given so if bryostatin or its new derivatives show an actual improvement, then we'll know what we have, and we'll know that the drug can be given much sooner for less damaged synapses as our management team has pointed out. It's simply how our MOA works.

Even if the hoped MOA doesn't pan out, will be interested in seeing the results of genetic damage in patients which could also be an explanation for Jeni and CU patients. Looks like the company is signing on some well respected researchers. That alone is extremely interesting and hopefully a promising sign going into 2018. JMHO
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