P being labeled the "riskiest" drug among our 3 is like taking three Triple Crown winners and saying which is the "riskiest" as to quality. They all are super drugs and super horses, but some go beyond even that term to super-duper and that IMO more defines Kevetrin and Brilacidin.
If P is our riskiest drug, I will take that gladly to the bank.
IMO the great divide on this board is between those that talk about P as being either everything or nothing whereas the other side believes it will be at worst better than anything currently available when all factors are considered. I say this as even though the efficacy may lag behind biologics, the safety and cost issues should propel it ahead of them as being the first recommended by doctors and should it fail, then have the patient proceed onto the higher priced/ riskier as to safety biologic products.
Saying it only has to match Otezla is a slap in the face to Prurisol as it was already beating Otezla in the 200 arm as I believe was pointed out previously.