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Re: To infinity and beyond! post# 206717

Thursday, 12/07/2017 2:58:54 PM

Thursday, December 07, 2017 2:58:54 PM

Post# of 403543
Without seeing the trial protocol it is impossible to say if interim analysis was actually included. I wonder why would they need one.

The trial is a smallish and time limited (subject in and out in 16 weeks) - not like some cancer trials where small number of responders may keep the target event count out of reach for years. Also, the trial is not addressing imminently life threatening condition when early detection of futility is not only monetary but ethical question.

But then, IPIX keeps including anticipated interim results in their press releases at least until May 2017. I don't get it. I would like to hear Leo's definition of interim results. Interim results = preliminary analysis (?) of full data set ? Final results come out after dealing with outliers? I Just don't get it. But that is no news around where I am living.



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