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Re: dr_lowenstein post# 42220

Tuesday, 11/28/2017 10:14:51 PM

Tuesday, November 28, 2017 10:14:51 PM

Post# of 48316
Oncosec and Jounce have a pre clinical agreement through the Oncosec (TAP) program. Jounce is using Oncosec's GENESIS research generator and applicators to rapidly assess potential candidates in preclinical models. This agreement is less than 6 months old so it is fairly new. Maybe we hear some updates from Jounce on this sometime soon.

What I find interesting is that the CEO of Jounce is Richard Murray, who was the SVP of biologics and vaccine research at Merck ($MRK) prior to joining Jounce. Merck and Oncosec are currently collaborating on the PISCES trial. You can obviously see connections between these companies. It is just speculation but these connections could lead to bigger Biotech names like Celgene or Gilead showing interest.

What I also find interesting is the deep collaboration Jounce has with Celgene which includes solid tumors such as NSCLC, HNSCC, TNBC, Gastric, and also melanoma. Celgene's investment in Jounce may be worth up to 2.6 Billion dollars.

I would like to entertain the idea that if Jounce makes any progress using Oncosec's technology that there might be some sort of trickle down affect that might stir interest from Celgene and Jounce doing some kind of combo trial that would include using Oncosec's Generator and applicators.... and maybe just maybe a combo study with Oncosec and a multigene construct.

Nobody knows who the collaborator will be for PIIM construct, maybe Jounce and Celgene. Seems logical since Jounce already put a foot in Oncosec's door.