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Re: DewDiligence post# 211164

Tuesday, 11/28/2017 9:24:30 AM

Tuesday, November 28, 2017 9:24:30 AM

Post# of 251715
PFE/Merck KGaA—Bavencio phase-3 fails in gastric cancer:

https://www.prnewswire.com/news-releases/merck-and-pfizer-provide-update-on-phase-iii-javelin-gastric-300-study-in-patients-with-pre-treated-advanced-gastric-cancer-660493023.html

This trial compared Bavencio monotherapy to standard chemotherapy in third-line gastric cancer irrespective of PD-L1 expression. The primary endpoint was OS.

Bavencio is approved for bladder cancer (#msg-131199162) and MCC (#msg-129810893). It is alos being tested in NSCLC (#msg-118239759).

Please see #msg-135830618 and #msg-108253419 for related info.

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