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Saturday, November 25, 2017 7:28:46 PM
Although Dr. Fraser was vital to the science behind Monster silk, his piggybac transposon is not the strength of the patent. in fact, it's not even in any of the 30 claims of the invention.
It's Dr. Don Jarvis' genetic "cassettes" with Kraig Labs polypeptides that hold the power. You can read the brief description in paragraph 17 of the patent. Even the first claim of the invention is the actual polypeptide, not the piggybac vector used to insert it.
Essentially, the polypeptides being patented is the snippet of spidersilk gene flanked by the silkworm genes that guide it to the correct spot in the silkworms DNA.
Any gene editing tool (ie, CRISPRs, TALENS, piggybac, zincfingers) will need to use those polypeptides to insert spidersilk into a silkworm.
Kraig Labs can patent that polypeptide because it's chimeric, so it is not found in nature.
It's all in the patent application if anybody takes the time to read it.
This is all assuming the patent is granted. But even patent applications have protections.
P.S. Jazz - If you have a better way to explain it, please do. Thanks
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