PTLA -4%/AH—PDUFA date for Bevyxxa CMC issue delayed until 1/30/18: https://finance.yahoo.com/news/portola-pharmaceuticals-provides-bevyxxa-betrixaban-232243167.html The reason the stock isn't down more than 4% is that PTLA previously warned that the CMC issue might not be resolved until 1Q18.