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Sunday, 11/19/2017 9:37:56 AM

Sunday, November 19, 2017 9:37:56 AM

Post# of 346050
Don't know if this article was posted already (published 11/3/2017), excellent overview of Ovarian cancer.

A Comprehensive Overview Exosomes in Ovarian Cancer

Especially like this section. At least PPHM's exosome proof of concept is getting recognition.

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With the exception of proteins and miRNAs, several bio-active molecules such as phosphatidyl-serine (PS), DNAs, glycans, and glycoprotein [44], have been reported to play an important role in exosome internalization, signal recognition, and novel vaccines. Early evidence suggests that uptake of OvCa derived-exosomes by NK cells requires PS at the exosomal surface, but the presence of PS is not sufficient [8]. The latest study by Jayanthi Lea et al. also provides proof of concept data supporting the high diagnostic power of PS detection in the blood of women with suspected ovarian malignancies [45].



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