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Friday, 10/27/2017 8:24:16 PM

Friday, October 27, 2017 8:24:16 PM

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"After comprehensive review of the market opportunity for treatment and prevention of shingles, all of which points to a changing epidemiology of shingles, highlighted by a diminished occurrence of post-herpetic neuralgia (PHN) in patients with shingles, we have decided to discontinue the Phase 3 trial of Valnivudine™, the company’s investigational drug being developed to reduce incidence of PHN. The approval of a second herpes zoster vaccine, along with
continued success of Zostavax, is expected to further reduce the incidence of shingles and corresponding numbers of patients with PHN. This decision to discontinue the Phase 3 study also enables us to utilize available capital to further advance our HBV pipeline, where we see a far higher potential return on investment for our shareholders."



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