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Post# of 252311
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Thursday, 10/26/2017 6:00:06 AM

Thursday, October 26, 2017 6:00:06 AM

Post# of 252311
PBD.AS / PRBGF / PB9.F (Novel AD approach)

Has anyone here heard of Probiodrug AG? I just came across them seeing this press release
http://globenewswire.com/news-release/2017/10/26/1153732/0/en/Probiodrug-to-Present-Data-from-its-Phase-2a-SAPHIR-Study-at-International-Alzheimer-s-Disease-Conference.html

Which led me to their website and their 2A (short 12 week) results released in June of this year
http://www.probiodrug.de/probiodrug-announces-encouraging-results-of-the-phase-2a-saphir-study/

I don't have a science background and haven't dug into PubMed yet to know if their approach has a sound basis. This is from their website:

"Probiodrug is developing drug candidates to specifically target toxic pyroglutamate-Abeta (pGlu-Abeta) via two complementary modes of action:
(i) inhibition of Glutaminyl Cyclase (QC), thus inhibiting the production of pGlu-Abeta; and
(ii) clearing existing pGlu-Abeta from the brain."

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