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Re: DewDiligence post# 34418

Monday, 09/25/2006 7:02:00 PM

Monday, September 25, 2006 7:02:00 PM

Post# of 252496
What GPCB did was to increase the number of PFS events in the unblinding trigger beyond the value originally specified in the SPA.

Then, this would have no effect on the survival result. Patients still cross over whenever they progress. What this did do was to increase the power for the PFS endpoint itself since there were more events to work with (less censored patients).
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