Powerball numbers for 10/21/2017 are: 14 41 42 45 69 Powerball 4 Powerplay 2X The estimated Grand Prize was $174,300,000 ($109,000,000 cash). There was no Grand Prize Winner. The next Powerball drawing will be on Wednesday, October 25th, 2017 with an estimated Grand Prize of $191,000,000 ($119,400,000 cash). http://www.powerball.com/pb_home.asp