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Re: DewDiligence post# 214404

Wednesday, 10/18/2017 7:10:52 PM

Wednesday, October 18, 2017 7:10:52 PM

Post# of 252311
QURE / BMRN:

The poster is here
http://uniqure.com/ESGCT%20Huntington%20mouse%20model%20poster%20FINAL.pdf

I've been selling my position for a while (mostly at prices BELOW today's close). I should post an update as to my thinking sometime but in a couple weeks I should be completely out and it may be better to bash management then smile.

I was out during the BMRN hemophilia talk and only caught bits and pieces by cell phone but the part I heard talked about trial design and they said 4 year safety follow up I didn't hear if they clarified it in the Q&A or not. SO I am not sure if the agency(ies) are requiring that to file or if they could file on 1 year end point alone.... If the former I'd say that is a good reason for QURE to be down on its own.
http://investors.biomarin.com/download/FINAL_BioMarin_R%26DDay2017.pdf (Slide 118 is trial design)

Also on R&D Day doc seemed to downplay interest in 5-10% factor expression. BTW BMRN guided down revenue for Q3 because of delays in ordering in Brazil related to economic instability there. They said were informally told they'd receive order in Q4 if so revenue would be in middle of guidance if not would be lower.

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