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Re: scottsmith post# 196762

Thursday, 09/14/2017 12:47:54 PM

Thursday, September 14, 2017 12:47:54 PM

Post# of 403241
Agree with your line of reasoning here SS.

Have thought from the get-go that the timing of the interim analysis, at a point when most of the trial is complete, was odd; so have always been curious as to its intent.

If the interim thinking was to "look for a signal", they may very well have their signal via the unblinded data to-date and have forgone the intermediate analysis for integrity reasons as claimed. This IS the money trial for P. Might be just as simple as that.

Simple question: why wasn't the interim update done sooner, before trial integrity might be an issue?

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