Wednesday, September 13, 2017 10:20:22 PM
Sol-Gel Nasal Delivery
Soft gels have become a popular delivery mechanism since they are easy to administer, familiar to patients, and may contain a variety of different chemicals designed for slow-release and other features that improve the safety and efficacy profile of the active ingredients.
PreveCeutical Medical Inc.’s (CNSX: PREV) Sol-Gel technology encapsulates cannabinoids in a soluble form, while nanomicelles provide tissue permeation enhancing properties. Local tissue irritation is avoided as cannabinoids are in-solution and can be presented at lower doses. At the same time, Sol-Gels can remain in place for extended periods of time, which can reduce the administration times to once or twice weekly rather than daily.
The company has pioneered a novel process for preparing insoluble drug-containing nanomicelles and incorporating them into Sol-Gels in conjunction with the Parekh group at PACE-UQ. The team plans to file a provisional patent application around the single phase Sol-Gels for nasal delivery, which could vastly improve bioavailability relative to other therapeutics that are already on the market.
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