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Thursday, August 31, 2017 2:38:02 PM
- Hyalolex for Alzheimer’s and other cannabis-based drugs for pain, epilepsy, and more are raising the market valuation growth potential for IGC
- Phytocannabinoids target protein receptors in the brain, peripheral nervous system and other parts of the body, including the lungs, liver, and other organs
- Cannabidiol makes up as much as 40 percent of cannabis-plant extract and has more potential medical uses than THC
Cannabinoid receptors have been known in the medical community since 1988. India Globalization Capital, Inc. (NYSE MKT: IGC) is the first company to develop revolutionary cannabis-based pharmaceuticals targeting Alzheimer’s. Based on this alone, the company’s market valuation growth potential is high, given the possibilities now recognized for these compounds. IGC has a deep pipeline of products, including recently announced therapies such as IGC-501, for arthritic and neuropathic pain; IGC-502 for canine seizures; and IGC-504 for cachexia, a syndrome often associated with debilitating diseases such as multiple sclerosis, Parkinson’s and cancer.
The potential for growth is strong, as cannabis companies such as Anavex Life Sciences Corp. (NASDAQ: AVXL), AC Immune Ltd. (NASDAQ: ACIU) and others have seen market valuations in the hundreds of millions of dollars and even higher.
While there is no cure for Alzhimer’s, therapies, such as the one IGC is pursuing for Alzheimer’s, hold promise in addressing the disease. Phytocannabinoid treatments are also effective because of the protein receptors in the brain and other tissues of the body. There are several different types; one includes the G protein-coupled receptor family, activated by endocannabinoids the body synthesizes when under stress. These receptors play a role in pain modulation, appetite, mood, and even memory.
There are also CB1 receptors, which are thought to be expressed at the synapses in the brain. They have also been found in the peripheral nerves and in muscle, liver, and lung tissue, as well as in fat. Aside from being associated with pain regulation, these cannabinoid receptors have effects on emotion, sensory perception, memory, cognition, and movement. Some autonomous functions are affected as well. Found in the immune system, CB2 receptors have anti-inflammatory properties and other functions, being based in T cells and B cells. They have also been found in macrophages and hematopoietic cells.
Evidence suggests there are more types of cannabinoid receptors. The known types are activated naturally by endocannabinoids but can also be stimulated by compounds found in cannabis plants and by synthetic cannabinoids, which helped researchers identify the receptors in the first place.
Until recently, it was tetrahydrocannabinol that had the attention of mainstream media, known for its psychotropic effects. However, cannabidiol (CBD), which constitutes up to 40 percent of plant extracts, seems to have more medical applications. It’s widely believed to have anti-psychotic, anti-depressive, anxiety-reducing, and anti-convulsive effects. Therefore, CBD has the potential to be useful to the 50 million people around the world with refractory, or drug resistant, epilepsy; the 1.3 million individuals in the United States affected by cachexia every year; the 5.3 million people in the country with Alzheimer’s disease; and the millions who suffer from chronic pain.
For more information, visit the company’s website at www.IGCInc.us
Recent IGC News
- IGC-AD1’s Interim Phase 2 Data Show a Reduction in Alzheimer’s Agitation at Week Two • Business Wire • 04/16/2024 11:00:00 AM
- IGC Pharma Adds Advisor in Artificial Intelligence • Business Wire • 04/09/2024 01:00:00 PM
- IGC Pharma Announces $3 Million Unregistered Private Placement of its Common Stock • Business Wire • 03/26/2024 07:00:00 PM
- IGC Pharma Announces Positive Interim Results for IGC-AD1 in Reducing Alzheimer’s Agitation • Business Wire • 03/20/2024 03:00:00 PM
- IGC PHARMA Announces its Participation at the Benzinga Virtual Healthcare Summit 2024 • Business Wire • 03/20/2024 11:00:00 AM
- IGC Pharma (IGC): Healthcare Leader Terry Lierman Joins Board to Advance Alzheimer’s Pipeline • Business Wire • 03/12/2024 07:00:00 PM
- Promising Results: TGR-63 Enhances Memory in Alzheimer's Mouse Model • Business Wire • 02/28/2024 06:00:00 PM
- IGC Pharma Announces Equity Analyst Coverage by Ascendiant with a “Buy” Recommendation and $3.00 Price Target • Business Wire • 02/23/2024 05:01:00 PM
- IGC Pharma Reports Third Quarter Fiscal 2024 Results • Business Wire • 02/17/2024 12:05:00 AM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 02/14/2024 09:03:00 PM
- IGC Pharma Announces TGR-63 Reduces Agitation in Alzheimer's Mouse Model • Business Wire • 02/01/2024 02:20:00 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 01/31/2024 09:04:23 PM
- IGC Pharma Breakthrough: Preclinical Trial Data Shows TGR-63 Reduces Plaque in Alzheimer’s • Business Wire • 01/23/2024 02:20:00 PM
- IGC Pharma Activates ClinCloud, One of 12 Sites in Ongoing Phase 2b Alzheimer’s Trial • Business Wire • 01/17/2024 02:20:00 PM
- Form EFFECT - Notice of Effectiveness • Edgar (US Regulatory) • 01/09/2024 05:15:07 AM
- Form S-3 - Registration statement under Securities Act of 1933 • Edgar (US Regulatory) • 12/29/2023 09:54:29 PM
- Patent Granted to IGC Pharma for Groundbreaking Drug Formulation to Treat Agitation in Alzheimer’s • Business Wire • 12/19/2023 02:20:00 PM
- IGC Pharma Announces Participation in Biotech Showcase and BioPartnering @ JPM Alongside the J.P. Morgan 41st Annual Healthcare Conference 2024 • Business Wire • 12/13/2023 02:30:00 PM
- IGC Pharma Announces Collaboration to Integrate AI into Clinical Trials • Business Wire • 12/06/2023 01:30:00 PM
- IGC Pharma Announces Master Agreement with Leading South American University to Advance AI Initiatives • Business Wire • 11/21/2023 01:30:00 PM
- IGC Pharma Reports Second Quarter Fiscal 2024 Results • Business Wire • 11/13/2023 01:00:00 PM
- Form 10-Q - Quarterly report [Sections 13 or 15(d)] • Edgar (US Regulatory) • 11/09/2023 10:15:59 PM
- Form 8-K - Current report • Edgar (US Regulatory) • 10/27/2023 09:21:48 PM
- Form 424B5 - Prospectus [Rule 424(b)(5)] • Edgar (US Regulatory) • 10/27/2023 08:38:17 PM
- IGC Pharma Granted European Patent for Groundbreaking Cannabinoid-Based Pain Topical Relief Therapy • Business Wire • 10/19/2023 07:30:00 PM
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