ImClone Systems Inc (formerly IMCL)

[biophud]

Question for Pharma. Could you clarify your definition of basic science research. Are you saying that Imclone should only spend money on clinical trials?

I would describe the RON-kinase paper as an example of translational research (the type of researh that Imclone and other developmental stage biotechs should be doing--in my opinion). Basically, Imclone generated anti-RON antibodies, tested the effects on down stream signaling pathways, demonstrated in vitro effects on cells, and most importantly demonstated in vivo efficacy in mice.

In general, I have been impressed with the quality of the papers that Imclone has produced in recent years, and I think that the early stage pipeline is an underappreciated.

Any comments are appreciated. Thanks for your contributions to the board.

Biophud