Avid Bioservices Inc (CDMO)

[goodJohnhunting]

Biopharm and Phophoantigens,

The key initiators of V?9Vd2 activation are small, pyrophosphate-containing molecules called phosphoantigens (pAgs) that are present in infected cells or accumulate intracellularly in certain tumor cells

Well, well, well.. Is this a test or are you catching onto my theory?

Mevalonate pathway, AKA isoprenoid pathway, AKA HMG-CoA reductase pathway. The Statin target pathways and inhibitor MOA.

And drum roll....... V9Vd2 TCells are activated by phosphoantigen to tumor cell receptors via the Mevalonate pathway, or AKA the Isoprenoid pathway, or better known as the HMG-CoA pathway.

Would an inhibitor such as statin have an effect on these accumulated phosphoantigens??

Very interesting and coincidental abstract?

All the best,
John