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Alias Born 07/02/2017

Re: None

Sunday, 07/23/2017 10:24:06 PM

Sunday, July 23, 2017 10:24:06 PM

Post# of 18649
1615EpCAM133

TetraKE for solid tumors, which will enter the clinic after the TriKE molecule CD16/IL-15/CD33.

Again like the TriKE molecule for liquid tumors (targeting mainly AML). TetraKE looks to be a promising molecule for solid tumors (mainly for prostate, breast, and potentially colon cancer) this is because of the modified IL-15 crosslinker, which allows for NK cell proliferation.


The most promising piece of information about TriKEs and TetraKEs is that it targets carcinoma cells rather than any specific type of cancer cells. Meaning it has the TriKE platform can be used on a myriad of cancers subtypes.



For the previous post in regards to who will be the next CMO again, my guess is still Mace Rothenberg.



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