Biotech Values

[biomaven0]

You don't even get perfect concordance between different parts of the same tumor on biopsy or between tumors and mets.

The key for me is driver mutations, and I suspect that there would be better concordance with those than with incidental mutations. If you find an actionable driver mutation in a liquid biopsy, then that is indeed actionable. So the real question becomes how often those mutations are found in a solid tumor biopsy without showing up in a liquid biopsy.