Oramed Pharmaceuticals Inc (ORMP)

[Spideyboy]

Hi Thirdave,

Thanks for informing about Eastgate.

While I can see there is an overall similarity in making insulin orally bioavailable, I would say Oramed is substantially a better bet. Not simply based on the clinical phase of their oral products, or their distribution deal and milestone funding from the Chinese, but also quite simply on the science.

Oramed's delivery allows the delivery of insulin to the liver via the portal vein, which mimics a natural flow of insulin. Also the patents of Oramed and Eastgate would be completely different in the method of delivery so no concerns there.

Also Oramed is only 1 clinical trial away from potential approval of ORMD-0801 Type 1 with the cash to achieve this, and with excellent safety and efficacy Phase II data. It seems Eastgate has very little information on where they are at or if they even have pre-clinical data? It generally appears Eastgate would be a decade away from a commercially available insulin product, if there is any data to show that it works.

Finally going past just insulin, the beauty of Oramed's POD technology is that really they haven't created a new drug, they've just created a great delivery system. So as per their corporate presentation, Oramed can simply swap whatever drug it wants in and out of the fundamental POD system, and create a whole new orally bioavailable drug, which previously was only available via injection.

Again given the circumstances outlined, Oramed seems the better bet, short, mid and long-term. IMHO