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Thursday, May 25, 2017 2:37:54 PM
A compound taken from marijuana greatly helped some children with a severe and often deadly form of epilepsy and completely stopped seizures in a very few, researchers reported Wednesday.
It's a rare success in a field suffused with more hope than facts — in which advocates clamor to have marijuana and compounds taken from the herb legalized for free use, while government rules limit use and researchers struggle to prove what works and what doesn't.
[Study: Medical Marijuana Helps Children Who Have Seizures]
Study: Medical Marijuana Helps Children Who Have Seizures 1:38
In this study, the researchers enrolled kids with Dravet syndrome, a very rare and often deadly form of epilepsy caused by a genetic mutation. These kids have multiple, prolonged seizures that cause brain damage.
There's no treatment.
"It's hard to portray how serious and devastating this is," Dr. Orrin Devinsky, director of the New York University Comprehensive Epilepsy Center, told NBC News.
Devinsky and colleagues around the country tested a cannabis derivative called cannabidiol — CBD for short — on 120 Dravet syndrome patients.
Half took it for 14 weeks and half got a placebo.
"“It’s like a different human being in front of you.”"
"Seizure frequency dropped in the cannabidiol-treated group by 39 percent from nearly 12 convulsive seizures per month before the study to about six; three patients' seizures stopped entirely," the team wrote in the New England Journal of Medicine.
"In the placebo group, there was a 13 percent reduction in seizures from about 15 monthly seizures to 14," they added.
Quite remarkably, 5 percent of the children in the active treatment group with CBD were completely seizure free during the 14 weeks of the trial," Devinsky said.
"And these were kids who were often having dozens of seizures, if not many more than that per week."
http://www.nbcnews.com/health/health-news/cannabis-drug-reduces-seizures-severe-epilepsy-cases-n764381
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