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Monday, 05/15/2017 5:57:37 PM

Monday, May 15, 2017 5:57:37 PM

Post# of 21523
Full 2a trial article. Some incredible and interesting data in that report.

http://content.iospress.com/articles/journal-of-alzheimers-disease/jad170161?resultNumber=0&totalResults=3&start=0&q=neurotrope&resultsPageSize=10&rows=10

Now this is a quality of life improvement. Compassionate use patient #3

"Within 3?h of the first infusion, Subject #3’s MMSE rose from a baseline of 3 to 12. The MMSE score remained within the 10–12 range for 1-2 weeks, and remained between 5 and 12 thereafter (Fig. 4, green). These improvements of the MMSE roughly paralleled the changes of the ADCS-ADL. Improvements in cognitive function early in the course of treatment were also noted by the health care workers and caregivers. The patient, who had previously been largely immobile and absorbed in constant hallucinations that had occurred for many months prior to the bryostatin trial, became free of hallucinations, became mobile, able to feed himself, care for bodily functions, speak and recognize words, interactconversationally with others, and engage successfully in complex physical activities such as swimming and billiards. CIBIC-Plus score returned to ‘minimally improved’ after 7 months. By 9 months, the MMSE score declined to 5. As dosing became much less frequent his deficits and symptoms, including hallucinations, returned. Treatment was terminated when caregivers requested a change to a different residential facility."
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