As I understand, the push back is only done to accommodate the hospital's IRB approval. The company is sitting on its hands waiting for this to come in over the next 4 weeks (maybe sooner). Unfortunate, but this is aspect is out of their control. They need to wait for the IRB meetings and the board to review and approve the study. They can't commence the trial before that.
I understand that patients are being pre-screened/pre-registered for the study at this time so once the IRB is approved the trial will start immediately and with only a 10 patient study this should be done fairly quickly I would Imagin (pun intended).
The cancelled options are likely some consultants that received options as part of their compensation and their scope of work was reduced. Either way, it means less dilution so the exact reason is not that important (IMHO).
JB
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