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biomaven0

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biomaven0

Re: zipjet post# 210209

Tuesday, 03/28/2017 9:40:47 AM

Tuesday, March 28, 2017 9:40:47 AM

Post# of 252477
SM is largely driven by PDGFR, while GIST is largely driven by KIT.

Frontline KIT is handled well by Gleevec - it's only the mutations engendered by prolonged treatment that require a different drug. The BPMC drug would work well in frontline GIST driven by PDGFR, but that's a small fraction.
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