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Re: Virgil Hilts post# 50282

Tuesday, 08/29/2006 12:58:24 PM

Tuesday, August 29, 2006 12:58:24 PM

Post# of 82595
Virgil,

Slowly now.

The reason that the discussion revolved around what Ovanome was, is that Ovanome has not changed. It is still the same product that was tested on 80 patients several years ago. It is still the same product that supposedly went into Moffit's assessment program and never came out. It is an old unfinished and unused product.

The reason that Ovanome does not apply to the NeoCodex PR is that the NeoCodex program is specifically new research. Research into identification of the genes associated with the various drug reactions. Ovanome doesn't do that. It never has. If you change it to accomodate such a function it will not be Ovanome it will be something else.

I find it interesting that you do not see any significance in the obvious omission, by DNAG management, of any mention of Ovanome in the PR. Do you think they would miss an opportunity like that? An opportunity to promote one of their products. Even I give them more credit than that.

Ovanome identifies a specific pattern of snps from a high density snp panel and selects which patients will have a greater chance of benefiting from a specific drug therapy. These patterns are chosen statistically from several thousand possible patterns based on their predictability, not on their association with the genes responsible for the drug response.

The NeoCodex PR states that DNAG will use their platform to identify the specific genes associated with the various responses. These are not the same thing. I repeat, not the same thing.

I'm sure that your penchant for skimming the various high points of the technology and selecting those facts that you 'like' has provided you with some level of understanding. A simplistic level that assumes that any snp that appears in a statistical study of a drug response must be related to the gene in question, but you would be completely wrong. There is no direct link necessary between two such components. The concept of AIMs and how they work should have 'clued you in' to that.

regards,
frog