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Post# of 253527
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Alias Born 02/27/2007

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Tuesday, 02/28/2017 2:10:28 PM

Tuesday, February 28, 2017 2:10:28 PM

Post# of 253527
Good Kyprolis result for AMGN - impacts LGND too:

Amgen (AMGN) today announced positive results from a planned overall survival (OS) interim analysis of the Phase 3 head-to-head ENDEAVOR trial. The study met the key secondary endpoint of OS, demonstrating that patients with relapsed or refractory multiple myeloma treated with KYPROLIS® (carfilzomib) and dexamethasone (Kd) lived 7.6 months longer than those treated with Velcade® (bortezomib) and dexamethasone (Vd) (median OS 47.6 months for Kd versus 40.0 for Vd, HR = 0.79, 95 percent CI, 0.65 – 0.96).

http://finance.yahoo.com/news/phase-3-head-head-trial-140000117.html

The 3% royalty LGND gets might well hit around $2/share in a year or two. And it's worth noting that any generic will very likely also need to license the captisol ingredient, so should be no patent cliff.

Peter

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