Friday, February 24, 2017 11:48:36 AM
"We are very pleased to have achieved successful completion of all our objectives in the Phase 1 portion of this trial which established safety across all doses tested, and demonstrated preliminary evidence of clinical activity, including durable responses of over one year in two of the evaluable patients so far," stated Mark Cornfeld, M.D., Idera's Medical Lead, Oncology. "Additionally from a scientific standpoint, we've established proof of mechanism through our translational effort which has gone well beyond the norm compared to what is typically done in oncology drug development."
Continued Cornfeld, "At this point we have very clear justification to further the development of IMO-2125 and we'll soon be moving to the phase 2 portion of the trial, which will expand to multiple centers. Additionally we are undertaking a parallel development pathway for IMO-2125 in combination with pembrolizumab and while that is not the focus of this presentation today, we are making good progress with safety and dose evaluation in that arm."
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IDRA
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