Wednesday, February 08, 2017 2:59:52 PM
Who knows, perhaps only 12 weeks is needed for synaptic regeneration? Maybe we will later learn that burst exposure is what is needed. Alternating 12 weeks on and then 12 weeks off, in order to reset PKC activation?
Yes, there is a lot to learn and a lot of work still to do, but I'm hopeful there will be some meaningful results in a few months.
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I took the liberty of extracting more text from the same article you cut-and-paste from:
https://www.revolvy.com/main/index.php?s=Bryostatin%201&item_type=topic
Neurological
Bryostatin 1 has appeared very promising in enhancing memory in animal models. It was able to increase the duration of memory retention of the marine slug Hermissenda crassicornis by over 500%.[7] Additionally it also increased the rate of learning in rats.[8] This makes it a possible drug candidate for the treatment of Alzheimer's disease. As of 2014, bryostatin 1 is in clinical trial phase II for the treatment against Alzheimer's disease.[4] [9]
The ability of bryostatin 1 to alleviate brain damage in ischaemically brain-injured rats also seems promising and may open another therapeutic field for bryostatins.[10] [11]
A phase II clinical trial (running from 2015 to 2017) is comparing two IV doses over 12 weeks against placebo for Moderately Severe to Severe Alzheimer's Disease.[12]
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