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Tuesday, 02/07/2017 2:53:11 PM

Tuesday, February 07, 2017 2:53:11 PM

Post# of 21540
Neurotrope says its reversed severe Alzheimers! However, conspicuously I can't find the testing results for these 3 patients that have a genetic condition that gave them Alzheimers much earlier than usual. They're not even typical Alzheimers patients. Why did Neurotrope pick these patients that have a variant of Alzheimers instead of garden variety Alzheimers patients? Where are their MMSE scores? If they were any good you know Neurotrope would announce that to get investors. Ironwood did this with their constipation drug Linzess this past year. Said last summer a reduced dose still produced great results in pivotal trial w/fewer side effects. But they didn't release the results, the numbers. Finally did last month and they underwhelmed and the stock tanked. Also, Neurotrope only monitored those 3 patients for 3 months! Based on that, donepezil cures Alzheimers! Donepezil's charts for all its endpoints look great at 3 months! Clear cut improvement with the numbers to prove it! Buuuuut, if you track those Donepezil patients past 3-6 months, their scores and condition plummet. Heck, even placebo groups look improved in most trials at 3 months. That is such a short time frame to say a drug reverses Alzheimers disease. What is Neurotrope basing that on? And this PH 2b trial they're running is again only 3 months! Seriously? It is easy for the existing 5 drugs that are already approved to show improvement at 3 months, sustaining or increasing that improvement beyond 3 months is the tricky part.
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