Saturday, January 14, 2017 10:31:38 PM
The p-value data from 3 months to 6 months gets better compared to placebo. While not all 6-month data is significant the data is for 6 months or 24 weeks. Most of the trials are designed for longer periods of time. For example the NASH fibrosis trial is designed for 72 weeks or 18 months. think of it this way. Emricasan mechanism action is that the drug works the more a patient takes it. If it gets close to statistical significance at month 6 what do you think will happen by month 18? If you said improve you would be correct. Although it will need to be tested to see how many months. It could be possible that statistical significance is reached by month 9. That is what is being tested and we will know once more data is out.
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