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Friday, January 13, 2017 4:00:18 AM
Just as Commercial Embeda could not be made stable it is now looming big nor can Commercial Troxyca be made stable.
The high tmperature and high pressure in the barrel of the extruder, needed for fusion does serious wall damage to the polymers encased opioids so that the resulting drug is unstable and will have serious life threatening dose-dumping problems in the patient's body fluids.
The exact reason why Embeda was withdrawn for 4 years. The more Naltrexone quantity ratio to be extruded and the higher temperature and pressure results which thereby cause even more polymers wall damages.
This is the exact reason that Purdue never went Commercial with their technology. Purdue owns the Embeda technology and not Pfizer/Alpharma/King which were sued successfully for Patent Infringement.
"Just as Commercial Embeda could not be made stable it is now looming big nor can Commercial Troxyca be made stable." Hence the "Russian Roulette" risk every time one took the drug.
$ELTP SequestOx technology is very simple, low temperature, low pressure tech so that every capsule of the two-bead drug is stable every time.
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