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[MinnieM]

Research on Niagen/Nicotinamide Riboside/NR showing why it is superior to other forms of vitamin B in raising NAD+ levels:

An approximately 200-page thesis published in Iowa Research Online, the University of Iowa's Institutional Repository. Abstract says 190 pages, but when I open the document, I get 208 pages. It's a good read. http://ir.uiowa.edu/etd/3203/

Quote: “NR contributed to the intracellular NAD metabolome more rapidly than NMN and increased NAD+ by more than 2 fold after 24 hours, indicating NR is kinetically superior to NMN. In line with the intracellular findings, extracellular NMN rapidly and dramatically decreased over 24 hours as extracellular NR rose.” End quote

Quote: “Nicotinamide riboside (NR) is in wide use as an NAD+ precursor vitamin. Here we conducted experiments to determine the time and dose-dependent effects of NR on blood and liver NAD+ metabolism in people and mice, respectively. We report that human blood cell NAD+ can rise as much as 2.7-fold with a single dose of NR, that NR elevates mouse hepatic NAD+ with distinct and superior pharmacokinetics to those of nicotinic acid (NA) and nicotinamide (Nam), and that single doses of 100, 300, and 1000 mg of NR provide a dose-dependent increase in the blood cell NAD+ metabolome in the first clinical trial of NR pharmacokinetics. We also report that nicotinic acid adenine dinucleotide (NAAD), which was not thought to be en route for conversion of NR to NAD+ , is formed from NR and that the rise in NAAD is a highly sensitive biomarker of effective NAD+ supplementation.” End quote

Also, take a look at http://aboutnr.com/

Clinical Trials: https://clinicaltrials.gov/ct2/results?term=nicotinamide+riboside&Search=Search&flds=abcefgps

I started taking the combination of Niagen and Pterostilbene that Elysium sells, but, happily switched suppliers a few months ago. Here's what I order now:

Niagen from Thorne Research
https://www.amazon.com/Thorne-Research-Nicotinamide-Supplement-ChromaDex/dp/B01FIJAW8M?th=1

Pterostilbene from Jarrow
https://www.amazon.com/Jarrow-Formulas-Pterostilbene-Cardiovascular-Neurologic/dp/B005ACNW5S/ref=sr_1_1_s_it?s=hpc&ie=UTF8&qid=1483995763&sr=1-1&keywords=Jarrow%2BFormulas%2BPterostilbene&th=1

I'm not holding shares at this point in time... my interest has been due to following Niagen research for several years now.