• Amgen has tied the knot with Germany’s Immatics, paying $30 million upfront and offering hundreds of millions more in possible milestones for the development of bispecific T cell-engaging therapeutics for a range of cancers.
• Just weeks after ImmuNext signed Roche up as a partner, Sanofi has stepped on board to partner on a preclinical CD40L antibody for autoimmune disease that has potential in treating multiple sclerosis and lupus. The deal is worth a potential $500 million, though it likely starts out on the small side.
• Incyte and Merck are kicking off a slate of new pivotal studies for their combination of Keytruda and the IDO1 inhibitor epacadostat. They are expanding their pact to include non-small cell lung cancer, renal cell carcinoma, bladder cancer and squamous cell carcinoma of the head and neck.