Biotech Values

[biomaven0]

>>Has anyone come up with a (credible) theory that Alzheimer's is more than one distinct disease or perhaps has multiple factors that lead to the later stage symptoms?


Maybe ALS is a good analogy. There are currently seven distinct genes that are currently known to cause familial ALS. The genes are mostly all quite different from each other, although you can kind of see how most (but not all) might have something to do with protein disposal. So basically familial ALS must be multiple diseases ending in a common pathway (as the eventual brain pathology is indistinguishable).