Vid, TC, Jess, BioRocks, et al, Count me in as thinking that Denner has been the one "catalyst" to guide Ariad from a very precarious position to now one of strength.
He made some really gutsy decisions and executed many difficult tasks (CEO, BOD, Management changes, partnerships, drug roll out, areas to focus) in a way that instills confidence.
And look at all of the "smart money" institutions and hedges that have followed him as he has lead the way. Yes, he has a lot to gain from his 12M shares (Sarissa) yet he has invested a lot of time and effort into turning Ariad around in creating a winner that IMHO is pure genius. As I have opined before, he is not perfect and I am sure that he could honestly point out things that he might have done differently as that the nature of doing things differently and making gains.