OncoSec Medical Inc (ONCSQ)

[Titan V]

To be fair, those "scientists" were defending the time immemorial belief that the earth was flat. The very few astronomers who were trying to prove these guys wrong were the ones being ridiculed.

As for the PD1 receptor situation you describe, as I do not have a science background, I would like to use a simple analogy to explain what I think hschlauch is trying to suggest, and what ONCS and KU Leuven are perhaps trying to accomplish.

Imagine the tumor cell as a computer, PD1 receptor as its CD drive, and the checkpoint inhibitor as a CD with valuable information that we want to feed into the tumor cell. Are we absolutely sure that we will never be able to find another means to feed the information contained in the CD to the computer? Perhaps we could use a USB cable to feed the same information directly. You get my gist.

Lastly, and not the crux of my argument, and not always but sometimes, dismissing ideas just because they do not come from people with scientific expertise, might not alway be productive. We all know how a patent office clerk turned the world of physics upside down with his groundbreaking papers in the early 1900s. Not comparing the OP to this person by any means, just saying ideas could come first as thought experiments and the science to back them up may, or may not, come later.