OncoSec Medical Inc (ONCSQ)

[hschlauch]

I would be extremely surprised if ONCS doesn't use Heat Biologic's comPACT platform and combines it with EP IL-12 and pembrolizumab. The preclinical data just reported by HTBX at SITC is too huge to ignore in my opinion. The reported antigen-specific t-cell expansion in peripheral blood and spleen, along with the memory precursor cell improvements, is incredible.

Using an EP version of comPACT DNA with IL-12 DNA and pembrolizumab should theoretically lead to neoantigen-specific t-cell expansion, thus potentially increasing PD1/CTLA4-hi-positive TIL necessary for improving responses.