Mast Therapeutics, Inc. (MSTX): All Big Pharma failed in HFpEF. (Heart F...

Reply Private New

Next 10 Prev Next

Send PM Follow Ignore

Followers	1
Posts	206
Boards Moderated	0
Alias Born	04/06/2013

lux1

Re: None

Thursday, 10/27/2016 4:10:29 AM

Thursday, October 27, 2016 4:10:29 AM

All Big Pharma failed in HFpEF. (Heart Failure with Preserved Ejection Fraction)
Also the Pfizer trial completely failed in 2014 to demonstrate the efficacy of Sidenafil (Viagra) in HFpEF, Dr.Bourlag (AIR001 clinical investigator at Mayo) and others demonstrate that Sidenafil may even worsen the HF.
Novartis did the insane mistake to dump Aires when it was at the begin of AIR001 P2a due to a NVS business reorganization.
Merck and Bayer are involved in HFrEF. (Heart Failure with reduced Ejection Fraction) with the drug vericiguat, but with some doubts on efficacy and safety.
Now Novartis has Entresto a combo pill but always for HFrEF,it is effective in particular in the most severe cases.

AIR could be one of the winners in this competition and then a potential blockbuster.
An agreement, something between partnership and buyout, in this so important and empty field of HFpEF shouldn't difficult to achieve.
Obviously for a good CEO...