NanoViricides Inc. (NNVC)

[Rawnoc]

No they don't require it. Hence the word "should" and not "must." Then there is that pesky actual FDA code:

Code of Federal Regulations Title 21 PART 312 -- INVESTIGATIONAL NEW DRUG APPLICATION
https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?fr=312.23

It only asks for a vague description "if known," otherwise leave that section of the IND application blank.

This isn't a very difficult concept. Thank you, however, for links to Swiss companies and all sorts of other nonsense except for the FDA code itself which says zero about efficacy requirements -- because there aren't any.