corpus, In my opinion this continued collaboration is just some blow back from Mymetics on the new grant that Texas Biomed (Dr. Ruth Ruprecht) has received for over 20+ million and the design of the Mymetics study. Something smells rotten here. I believe the last study was designed to fail and Mymetics is pretty upset about it and has let them know they are not happy. This is just my opinion of course. It has never been explained why the dose of 70,000 times the average human HIV dose was used in first part of study. Mymetics points this out in last two PR's but never explains the reasoning. I have asked them in an email but have not received a response. My biggest question is; How can one mimic exposure form men to women if they increase the dose by 70,000, this makes no sense at all. Mimic means to imitate closely, 70,000 is not very close!
This was stated in the last two press releases, (almost word for word but not quite);
"The initial virus challenges of the study aimed to mimic the exposure of women to semen from HIV-infected men, although the viral dose of each of these seven animal challenges represented about 70,000 times the average human HIV dose passed during sexual intercourse from an HIV-infected male to an uninfected female.
During a second part of that study, the animal viral challenge dose was increased by 50% starting from the eights challenge onward, reaching more than 100,000 times the average amount of virus passed from an infected man to a female partner. At this virus dose, the vaccine did not show significant protection in the animals as the immune system was overcome."
