Clinuvel Pharmaceuticals (CLVLY)

[ghmm]

Nice recap. I follow the sharescene board too and have translated some of the government links. I'd certainly recommend that board for anyone with a position there are some posters who are really good at finding relevant info (along with a lot of noise posts too but its worth weeding through those)

Do you happen to know when Italy will start reimbursing at the new price? I don't recall seeing a date and since its a commercial price if Wolgen said that Scenesse is available under the access scheme I'd assume its not the commercial price but the old price.

I am thrilled EPP may not need a US P3 if they get it approved in the US I agree uptake and commercialization would be much quicker and the opportunity (# patients+likely higher price) would be greater than the EU opportunity.

Vitiligo will be a sizeable undertaking in terms of trial size/costs it would certainly be big if they could go directly to Phase 3 though I am not comfortable with their Phase 2 results to feel they can design a trial (right patient population/protocol) to succeed.

BTW, I don't agree with many of valuations/comps that I've seen on sharescene and google groups. One needs to take consideration of the launch phase/size of opportunity/likely competition, etc. I owned UTHR which was basically a one product company and while they were growing 30-40% annually they were over 10x sales. The first couple years of the launch a multiple of sales didn't make sense because of small numbers. Gentium was another one product company (similar circumstances in getting approval actually) they were sold for about 1B when sales (actually it was right around commercialization they were being reimbursed under compassionate use like Clinuvel) were in the 30M range if I recall. And like Clinuvel they had not yet gained US approval plus Sigma Tau owned the majority of US rights (which Jazz later purchased from them).