Ayala Pharmaceuticals Inc (ADXS)

[CATTDOGG12347]

BERKELEY, Calif.--(BUSINESS WIRE)--Aduro BioTech, Inc. announces that the United States Patent and Trademark Office (USPTO) has confirmed the patentability of its U.S. Patent 7,842,289 (‘289 patent) at the successful conclusion of an ex parte reexamination proceeding initiated by Advaxis Incorporated (OTCBB: ADXS). During the proceeding, the USPTO rejected Advaxis’ assertions of invalidity, and confirmed that the claims are patentable as originally issued and without amendment. The proceeding has now completed with the issuance of Ex Parte Reexamination Certificate US 7,842,289 C1 on November 1, 2011.

“We have built a broad portfolio of patents to protect our platform”
Tweet this
Aduro’s ’289 patent relates to Aduro’s proprietary Listeria monocytogenes (Listeria) platform that is used in Aduro's live-attenuated vaccine strains. Aduro’s technology enhances the expression of antigens by the bacterium, which in turn has been shown to increase potency of the induced immune response. “We have built a broad portfolio of patents to protect our platform,” said Thomas Dubensky, Chief Scientific Officer of Aduro BioTech, “and this reexamination provides further validation of the strength of our intellectual property position. We will continue to build the value of our IP portfolio as we advance our proprietary technology towards commercialization.”

Aduro’s intellectual property portfolio includes a number of issued patents, both in the United States and in various foreign countries, related to company’s proprietary Listeria platform. The intellectual property includes patents and patent applications directed to methods for attenuating the Listeria bacterium to improve its safety in vaccine