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Post# of 251892
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Re: bladerunner1717 post# 202776

Thursday, 07/21/2016 10:24:07 AM

Thursday, July 21, 2016 10:24:07 AM

Post# of 251892
One big caution is that Parkinsons trials are notoriously tricky - there can be a big placebo effect and there have been a litany of failed Phase IIIs after successful Phase IIs:

http://www.quintiles.com/blog/parkinsons-disease-and-the-placebo-effect

Here it is a bit worrying that "average total daily time of troublesome dyskinesia was not increased in one group and was decreased by 42% in the second group" - that perhaps suggests something going on with their trial design.

Peter



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